The Benefits of
Drug-Free Migraine Management

Pharmacological treatments may fall short for many migraine patients, highlighting the need for effective and tolerable care options. The Nerivio® REN Wearable is proven to provide effective migraine relief with no pills or needles and may serve as a safe first-line prescribed intervention.

The Benefits of
Drug-free Migraine Management

Pharmacologic treatments may fall short for some migraine patients, highlighting the need for effective and tolerable care options. The Nerivio REN Wearable is designed to provide effective migraine relief without medications and may serve as a safe first-line prescribed intervention.

Go Drug Free

Who Can Benefit the Most from a Non-Pharmacological REN Wearable for Migraine?

Nerivio may be an optimal migraine management option for the following patient groups:

a woman suffering from medication side effects
Children and Teenagers with Migraine

Younger patients often struggle with medication side effects, dislike taking pills, or fear injections.[1] The REN wearable offers a safe, non-invasive solution, empowering them to manage migraine effectively and independently in their daily lives.

Those Who Need to Reduce or Withdraw Medications:

Many individuals experience unpleasant side effects to migraine medications and some must even limit or stop using them due to health risks. Nerivio provides an alternative that eliminates these risks while delivering effective relief.

When Health Conditions Prevent Medication Use

Patients with comorbidities and underlying health conditions may find traditional migraine medications unsafe. Nerivio provides an effective option that avoids complications associated with systemic treatments.

When Occupation Limits
Medication Use

Individuals in safety-sensitive jobs, like police officers or heavy machinery operators, often cannot use medications that impair performance. Nerivio enables migraine management without compromising safety at work.

a woman suffering from medication side effects
Women in Their
Reproductive Years

Hormonal changes during menstruation, breastfeeding, and menopause can complicate migraine care. Nerivio offers a safe, drug-free alternative for women seeking relief during these sensitive phases.

a woman suffering from medication side effects
Veterans with Migraine-Related Challenges

Veterans often face unique health complexities, such as PTSD or risks associated with certain medications, making drug-free treatment essential. Nerivio offers safe and effective migraine relief without systemic side effects or dependence.

The Limitations of Pharmacological Migraine Treatment in Children and Teenagers

Adequate treatment during childhood may prevent chronic or refractory migraine in adulthood [2]. But, many children don’t like to swallow pills and fear injections. Others have difficulties sticking to their pharmacological treatment plans. In some cases, medication treatment may be delayed or even stopped due to unpleasant side effects, dosing issues, or rebound headaches [1].

Learn how Nerivio can help

A survey study found that the REN wearable empowers students to manage migraine attacks effectively, independently, and discreetly at school, significantly increasing in-school treatment rates and reducing barriers such as trips to the nurse’s office [3].

Rebound Headaches: A Hidden Risk of Over-Reliance on Migraine Medications

For individuals seeking relief from migraine, medication can feel like a lifeline—but excessive use of certain drugs may lead to a debilitating condition known as Rebound Headache or Medication Overuse Headache (MOH). Rebound Headache occurs when pain relief medications, particularly over-the-counter pain relievers, triptans, or opioids, are used too frequently. Instead of alleviating symptoms, these medications can actually cause more frequent and severe headaches, trapping sufferers in a cycle of dependency and pain [4].

By choosing a drug-free migraine treatment, you can break this cycle and reduce the risk of Rebound Headaches, allowing for effective migraine management without compromising your long-term health.

How can Nerivio benefit your migraine treatment?

Nerivio may reduce migraine medication intake, thus reducing medication side effects

Nerivio does not cause drowsiness, rebound headaches or systemic side effects

Nerivio offers on-the-go treatment, enhancing work performance and productivity

Nerivio allows adolescents to perform treatment in class without disruptions

Recent studies on triptans and CGRP mAbs reveal potential negative side effects

CGRP mAbs might cause hair loss and other unexpected side effects.

Source

People living with migraine who also have psychiatric disorders are likely to be non-responders to CGRP mAbs.

Source

There is a potential association between triptan initiation and an increased risk of ischemic stroke and myocardial infarction.

Source

Clinical Data Highlight:
Promising results suggest that Nerivio is effective as a stand-alone migraine treatment

A clinical study examining REN's impact among adolescent patients demonstrates promising results, indicating reduced medication dependency and improved migraine management outcomes (Esparham et al, 2023) [5].

Read the Study

Users Share Their Experiences on Reducing Medications

"Yes!! She uses it on the regular as a preventative, and any time she needs it as an intervention in the immediate to stop a forming migraine. She has been using it now for about 5 months now, and it continues to be the number one go-to, and has allowed her to almost completely get away from Sumatriptan, unless in a very severe (and now thankfully rare) episode.”
Brittany
Parent of Adolescent
"I have an intense fear of medicine and have extremely bad side effects to oral migraine medication. Using Nerivio has been a lifesaver. I use it more than any other medication I have. It really has changed my life."
Mathea D.
Adolescent user
"Nerivio has been tremendously helpful for my migraine management. Most of the time a Nerivio treatment is enough to stop my migraine, and I have been able to significantly reduce my reliance on my acute/"rescue" medications..."
Bari M.
Adult User
"Nerivio is a LIFE-CHANGER!! My daughter had one migraine that lasted over a year and a half. She tried everything even up to 7 medications a day to try to control it and nothing ever did... I cannot sing praise high enough for Nerivio!! I want to kiss the inventors!"
Charity
Parent of Adolescent
"Nerivio has been tremendously helpful for my migraine management. Most of the time a Nerivio treatment is enough to stop my migraine, and I have been able to significantly reduce my reliance on my acute/"rescue" medications..."
Bari M.
Adult User
"Nerivio works to reduce or eliminate my migraine pain without medication."
Janet B.
Adult User
"It works for headaches and dizziness some of the time. I like using it first before I take medication as it can reduce symptoms sometimes enough so that I don’t need medication."
Michele T.
Adult User
"Relaxing and effective. Helps reduce the use of medication. A much-needed reduction."
G.H.
Adult User
"Nerivio has cut down my migraine and medications."
Anonymous User
"Nerivio gives me control over my headaches. Using guided imagery and deep breathing, I experience relief without taking medication."
Anonymous User

Sources

  1. Taddeo D, Egedy M, Frappier JY. Adherence to treatment in adolescents. Paediatr Child Health. 2008;13(1):19-24. doi:10.1093/pch/13.1.19https://pmc.ncbi.nlm.nih.gov/articles/PMC2528818/
  2. Charles, J.A., Peterlin, B.L., Rapoport, A.M. et al. Favorable outcome of early treatment of new onset child and adolescent migraine-implications for disease modification. J Headache Pain 10, 227–233 (2009). Link
  3. Children 2024, 11(11), 1286; https://doi.org/10.3390/children11111286Hershey AD, Shmuely S, Stark-Inbar A, Asmar Y, Ironi A, Strong E, Kabbouche M. Patterns, Barriers, and Preferences of Treating Migraine Within the School Setting: A Survey Study of Students. Children. 2024; 11(11):1286. https://doi.org/10.3390/children11111286
  4. Scher, A., Rizzoli, P., & Loder, E. (2017). Medication overuse headache. Neurology, 89, 1296 - 1304. https://doi.org/10.1212/WNL.0000000000004371.
  5. Esparham A, Stark-Inbar A, Jekel L, et al. Acute Treatment of Migraine in Adolescents: Real-World Analysis of Remote Electrical Neuromodulation (REN). Pediatr Neurol. 2023;142:51-55. doi:10.1016/j.pediatrneurol.2023.02.008